Autoimmunity in uveitis
نویسندگان
چکیده
منابع مشابه
VITRECTOMY IN CHRONIC UVEITIS
Vitrectomy was performed on 25 eyes in 21 patients with chronic uveitis from various etiologies. Postoperative follow up averaged 22.8 months with visual improvement in 24 of 25 eyes. In this retrospective study, the techniques employed and the beneficial effect of vitrectomy alone or vitrectomy combined with cataract surgery (Iensectomy in most cases) on improving vision and decreasing th...
متن کاملProctor Lecture. Experimental allergic uveitis. Investigations of retinal autoimmunity and the immunopathologic responses evoked.
Waldon D. Uveitis is an inflammatory condition of the eye that is generally of unknown etiology. Although it may occur in association with systemic disorders, it most often occurs alone as a specific organ disease. It usually runs a chronic relapsing course that is difficult to manage clinically and may result in blindness. Infective agents as a cause have been established in only a few cases. ...
متن کاملNo Evidence of Association between Common Autoimmunity STAT4 and IL23R Risk Polymorphisms and Non-Anterior Uveitis
OBJECTIVE STAT4 and IL23R loci represent common susceptibility genetic factors in autoimmunity. We decided to investigate for the first time the possible role of different STAT4/IL23R autoimmune disease-associated polymorphisms on the susceptibility to develop non-anterior uveitis and its main clinical phenotypes. METHODS Four functional polymorphisms (rs3821236, rs7574865, rs7574070, and rs8...
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Gene association studies are less appealing in cancer compared to autoimmune diseases. Complexity, heterogeneity, variation in histological types, age at onset, short survival, and acute versus chronic conditions are cancer related factors which are different from an organ specific autoimmune disease, such as Grave’s disease, on which a large body of multicentre data is accumulated. For years t...
متن کاملRole of miR-146a in Immune System and Autoimmunity
MicroRNAs (miRNAs) are small preserved non-coding RNA molecules that regulate gene expression post-transcriptionally by targeting the 3' UTR of mRNAs for translational repression or degradation. The rising evidence has established the significant role of miRNAs within the regulation of immune system and the prevention of autoimmunity. MiR-146a has obtained an importance as a modulator of differ...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2018
ISSN: 1755-375X
DOI: 10.1111/aos.13652